Our common purpose – improving the lives of cancer patients and their families – inspires our innovative spirit, arouses our curiosity, and drives our relentlessness. We always work collaboratively and support each other, because we know that to transform patients’ lives requires our very best, each and every day.
Leadership
Stephen Bloch, MD
Position: Co-founder and Chief Executive Officer
As an entrepreneur, venture capitalist and former practicing physician, Steve knows firsthand the challenges of building successful healthcare companies. Unfazed by complexity in healthcare, whether scientific, regulatory, or market driven, Steve’s mission has been to make healthcare delivery more effective and affordable.
Before co-founding EvolveImmune, Steve helped start and finance leading healthcare companies as a general partner at Canaan Partners. Steve has served on the boards of companies in biopharma, digital health, medical devices and diagnostics, often as board chairman. Steve is currently chairman of the board at Liquidia (NASDAQ: LQDA), executive chairman of Allyx Therapeutics and is a member of Dartmouth Medical School’s Board of Advisors. Steve was BioCT’s Entrepreneur of the Year in 2023.
Before joining Canaan in 2002, Steve helped found and manage multiple start-ups, including RMS, one of the first radiology benefits companies where he was CEO for 6 years. Previously, Steve was a strategic pharmaceutical consultant for Arthur D. Little and a Ewing Marion Kauffman Fellow.
Steve obtained his AB from Dartmouth College, a MA in the history of science from Harvard, and his medical degree from the University of Rochester. Steve completed his residency at Massachusetts General Hospital/Harvard Medical School (radiology) and Lenox Hill Hospital/Cornell Medical School (internal medicine).
Stephen Bloch, MD
Co-founder and Chief Executive Officer
As an entrepreneur, venture capitalist and former practicing physician, Steve...
Jay Fine, PhD
Position: President, Research and Development
Jay brings over 30 years of drug discovery and development experience, including strong strategic leadership in discovery research, translational sciences and biomarker research covering immunology, immuno-oncology, inflammatory diseases and tissue fibrosis.
Prior to joining EvolveImmune, Jay was the Senior Vice President and Global Therapeutic Area Head for Immunology & Respiratory Diseases Research at Boehringer Ingelheim and the US Discovery Research Site Head at their Ridgefield, CT headquarters. Jay’s teams played seminal roles in the advancement of Skyrizi™ and Spevigo™, and delivered over 25 molecules into clinical development.
Previously, Jay held positions of increasing responsibility at Roche, Schering-Plough and the National Cancer Institute. He received his BS degree from Cornell University and his Ph.D. degree from the University of Rochester Medical Center. He is the author of over 75 scientific publications and patents, and has received numerous honors and awards throughout his career.
Jay Fine, PhD
President, Research and Development
Jay brings over 30 years of drug discovery and development...
Jeremy Myers, PhD
Position: Senior Vice President, Research and Development
Jeremy Myers leads EvolveImmune’s biology and biotherapeutic research teams.
Before joining EV Jeremy helped lead Pfizer oncology research and development in Pearl River, NY as senior director, head of the Integrative Biotechnology Group. He was a member of Pfizer Oncology Research and Development Leadership Team. During his tenure, Jeremy led development of tumor targeted immunotherapies leveraging antibody discovery and rational protein design, cell surface antigen discovery efforts and interrogation of biotherapeutic targets for antibody drug conjugates and T-cell retargeting bispecific antibody therapeutics.
Before Pfizer, Jeremy was a research faculty member and AstraZeneca Research Fellow in the Department of Biochemistry at Vanderbilt University Medical School. Jeremy received his BSc in biology from Bucknell University. He completed his Ph.D. studies in biochemistry and molecular biology at the LSU Health Sciences Center and Louisiana State University. He completed a postdoctoral fellowship at Vanderbilt University.
Jeremy Myers, PhD
Senior Vice President, Research and Development
Jeremy Myers leads EvolveImmune’s biology and biotherapeutic research teams. Before...
Jennifer Gabler, MBA
Position: Chief Financial Officer
Jen has over twenty five years of experience as a CFO for venture backed and startup companies.
As the CFO for Extraprise (now Vericast), a marketing services company, Jen built finance, HR, IT and back office operations plus helped lead global M&A efforts. She has also been the CFO for Aldea Pharmaceuticals and Butterfly Health, and provided financial project support for Marinus Pharmaceuticals (MRNS-NASDAQ) and Allyx Therapeutics. Jen began her career as an investment banking analyst at Merrill Lynch, and was the Northeast controller and a senior manager in entrepreneurial services at Coopers & Lybrand.
Jen co-founded The Refinery (www.refineryct.com), an accelerator for early stage companies with diverse management teams. She is also a founding partner of Marlborough Street Partners (www.marlboroughst.com) which provides strategic and operational services for investors and venture-funded companies.
Jen has an AB from Dartmouth College, an MBA from Columbia Business School and is a licensed CPA. She has been a lecturer and researcher at both Tuck and Harvard Business Schools.
Jennifer Gabler, MBA
Chief Financial Officer
Jen has over twenty five years of experience as a...
Michael Franken, MD
Position: Chief Business Officer
Michael brings over 25 years of biotech industry experience and strong business leadership in immunology, rare diseases, and transplant and hematology.
Prior to joining EvolveImmune, Michael was the Chief Business Officer at LogicBio Therapeutics Inc., a public biotech company focused on developing novel genomics medicines for patients with early onset genetic diseases. Until its acquisition by AstraZeneca, Michael was a member of the executive leadership team with responsibility for the company’s business development, strategy and commercial functions with a focus on executing strategic business deals, including the execution of several collaboration and license agreements with large pharmaceutical companies.
Previously, Michael co-founded and managed multiple biotech start-ups, and was in senior leadership roles at Momenta Pharmaceuticals (now Johnson & Johnson), Radius Health and Genzyme Corporation (now Sanofi). During his more than 10-year tenure at Genzyme, Michael held progressively senior positions in corporate development and deal making, drug development and as VP and General Manager, Transplant, was successful in driving significant growth of Genzyme’s commercial transplant business.
Michael received his MD degree from the University of Heidelberg, Germany and his Master’s degree in Health Policy and Management from the Harvard School of Public Health.
Michael Franken, MD
Chief Business Officer
Michael brings over 25 years of biotech industry experience and...
Mark Aimone, MBA
Position: Senior Vice President, CMC Development and Manufacturing
Mark Aimone brings over 30 years of CMC, supply chain and strategic sourcing experience, including operational leadership within R&D and manufacturing organizations. He has responsibility for building and leading EvolveImmune’s CMC development function and manufacturing operations.
Prior to joining EvolveImmune, Mark was Vice President at Alexion-AstraZeneca Rare Disease Business Unit where he built and led the CMC Leadership group. In addition, Mark had overall responsibility for the rare disease clinical supply chain including internal and external (CDMO) development, manufacturing, packaging, and distribution operations.
He joined Alexion in 2016 and played a pivotal role in bringing Ultomiris (ravulizumab, humanized monoclonal antibody complement inhibitor) into Phase 3 and approval in 2018. He chaired cross functional CMC governance and was a senior member of the Product Development and Clinical Supply Leadership team within Research and Development.
Prior to joining Alexion in 2016, Mark held positions of increasing responsibility at Pfizer in Groton, CT. Mark had responsibility for the CMC leadership groups for both Primary and Specialty Care at Pfizer and held clinical supply, strategic sourcing and technology transfer positions over his 20-year career. Mark received his Bachelor’s degree from Villanova University and his MBA from Rensselaer Polytechnic Institute.
Mark Aimone, MBA
Senior Vice President, CMC Development and Manufacturing
Mark Aimone brings over 30 years of CMC, supply chain...
Tony Fiorino, MD, PhD
Position: Senior Vice President, Clinical Development
Tony is a physician-scientist with over 25 years’ experience in the biopharmaceutical industry, including over 15 years as a drug developer and as a public and private biotechnology CEO and CMO, which followed a 10-year career as a healthcare analyst and hedge fund manager. Tony has run programs ranging from late-stage preclinical through phase 4 in oncology, inflammatory/immune disease, and neurology, across small molecules, biologics, cell therapies and medical devices, and brings extensive experience in both clinical development/regulatory strategy as well as study-level operational considerations, and provides hands-on and engaged program leadership. For the past two years, Tony has been an independent clinical development consultant, work with large and small biopharmaceutical companies on a variety of strategic and clinical development engagements, and before that he was Vice President, Clinical Development at Zentalis Pharmaceuticals.
Over the past 10 years, Tony has been deeply involved with multiple early-stage oncology programs and first-in-human oncology studies, which have included a BCL-2 inhibitor, a 3rd generation EGFR inhibitor, an Ikaros degrader, a non-CAR-T engineered T cell platform, and a dual-targeted monoclonal antibody, being developed in both hematologic malignancies and solid tumors. His prior roles include CEO of EnzymeRx (sold to 3SBio), Triumvira Immunologics, and BrainStorm Cell Therapeutics, and CMO of Immune Pharmaceuticals and electroCore. Before founding EnzymeRx, Tony was an analyst and portfolio manager at several firms including JP Morgan, Citigroup, and Pequot Asset Management. Tony received a BS in Biology from MIT, an MD and PhD from the Albert Einstein College of Medicine, and trained in medicine and dermatology at the Hospital of the University of Pennsylvania.
Tony Fiorino, MD, PhD
Senior Vice President, Clinical Development
Tony is a physician-scientist with over 25 years’ experience in...
Board of Directors
Kristen M. Hege, MD
A pioneer in immune-oncology, Kristen Hege has more than two decades of oncology clinical leadership in pharmaceuticals in addition to nearly three decades as a part-time clinical faculty member in the division of hematology at UCSF, where she cared for patients with blood cancers and other hematologic disorders. In her BMS role as SVP Early Clinical Development, Hematology, Oncology & Cell Therapy, she was responsible for advancing a pipeline of small molecules, biologics and cell therapies from first-in-human studies through clinical proof-of-concept. She led the 2Seventybio (formerly bluebird)-partnered BCMA CAR-T cell program (Abecma) in multiple myeloma from inception through FDA approval. Prior to BMS she held a similar role at Celgene as well as executive roles in biotech at Cell Genesys, Cellerant, and Theraclone. Dr. Hege currently serves on the Board of Directors of Mersana, Adaptimmune and Kelonia Therapeutics and as co-chair of the Biotech Committee for the Society of Immunotherapy of Cancer (SITC) along with advisory roles at cTRL, Moonlight, Dispatch, Cartography, Neomorph, Kamau and FL94.
In 2015, Dr. Hege was recognized by Fierce Biotech as one of the top 12 women in Biopharma, in 2019 by the Healthcare Businesswomen’s Association as a “Luminary” and in 2021 by San Francisco Business Times as one of the most influential women in Bay Area business. In 2022, she was recognized by UCSD with the Duane Roth Career Achievement Award for advances in science and medicine. Her career path and long history with CAR T cell development was featured as one of 25 physicians and scientists recognized as part of the 25th anniversary celebration of Nature Medicine and by Forbes magazine in 2022 as one of “50 women over 50: entrepreneurs” in recognition of her leadership role in the development of Abecma.
Dr. Hege received her MD at UCSF and completed internal medicine and hematology/oncology subspecialty training at Harvard and UCSF, respectively.
Kristen M. Hege, MD
A pioneer in immune-oncology, Kristen Hege has more than two decades of oncology clinical leadership in pharmaceuticals in addition to nearly three decades as a part-time clinical faculty member in...
Donmienne Leung, PhD
Donmienne Leung is a strategic thinker and influential drug hunter with over 20 years of experience in drug discovery. With a PhD in medicinal chemistry followed by a postdoc at Scripps in chemical biology; Dr. Leung then contributed in multiple pipeline programs at Eli Lilly. Currently, as a director at AbbVie Ventures, she leverages her scientific expertise to lead venture investments and serves as a board member in portfolio companies. She thrives on forming long-term relationships and networking with innovators and investors worldwide. AbbVie Ventures focuses on early-stage preclinical investments that align with core therapeutic areas and pioneering platforms to deliver novel drug targets or modalities in the future. Her greatest passion is drug discovery research and finding new medicines to meet patients’ unmet needs.
Donmienne Leung, PhD
Donmienne Leung is a strategic thinker and influential drug hunter with over 20 years of experience in drug discovery. With a PhD in medicinal chemistry followed by a postdoc at...
Denis Patrick, PhD
Denis Patrick is Vice President and Managing Partner at Pfizer Ventures. Dr. Patrick capitalizes upon his experience in evaluating external opportunities that are focused on areas that complement Pfizer’s Research interests to identify, invest and manage equity investments. He is currently responsible for managing investments in MISSION Therapeutics, Palleon Pharmaceuticals, FoRx Therapeutics, Kestrel Therapeutics, Anaveon AG, and EvolveImmune Therapeutics.
Dr. Patrick previously engaged in oncology research and oncology licensing activities for several large pharma oncology organizations, including Merck, DuPont Pharma, GSK and Pfizer. Dr. Patrick contributed significantly to several oncology drug discovery efforts that led to the approval of three marketed therapeutic agents including nelarabine, trametinib and dabrafenib. He also completed many licensing and acquisition agreements with large and small oncology focused biotech companies.
Dr. Patrick received his PhD in Biochemistry from the University of Pennsylvania.
Denis Patrick, PhD
Denis Patrick is Vice President and Managing Partner at Pfizer Ventures. Dr. Patrick capitalizes upon his experience in evaluating external opportunities that are focused on areas that complement Pfizer’s Research...
Ian Taylor, PhD
Ian Taylor is the President of Research and Development, and previously was Chief Scientific Officer, of Arvinas, the first clinical-stage biotechnology company based on targeted protein degradation. Previously he spent nearly 10 years at Pfizer Oncology, where he was an Early Development Team Leader, responsible for leading cross-functional drug development teams conducting Phase 1/2 clinical trials for multiple assets. His industry career started at Bayer Pharmaceutical, where Ian was employed for 12 years, ultimately as Vice President of Cancer Biology where he led the department responsible for all biology-related aspects of small molecule drug discovery of cancer therapeutics.
Dr. Taylor earned his BA from Bowdoin College and his PhD in Molecular Biology and Genetics at Harvard University and completed his post-doctoral training in the laboratory of Dr. Harold Varmus at the University of California, San Francisco and the National Institutes of Health.
Ian Taylor, PhD
Ian Taylor is the President of Research and Development, and previously was Chief Scientific Officer, of Arvinas, the first clinical-stage biotechnology company based on targeted protein degradation. Previously he spent...
Derek Yoon, MSF, MBA
As President & CEO, Mr. Yoon leads Solasta Ventures (formerly known as Aju IB Investment), one of the leading venture capital firms in South Korea. Based in Boston, Massachusetts, Mr. Yoon oversees Solasta’s investments with a focus on U.S. based life science companies and early-stage start-ups with novel science. Mr. Yoon also leads multiple cross-border strategic partnerships by leveraging his relationship with top-tier pharmaceutical companies in Korea. Currently, he is involved in multiple overseas venture capital fundraising projects by interacting with Korean governmental institutional funds as well as various private investors in Asia.
Additionally, Mr. Yoon is a board member of Arcellx, Carbon Biosciences, EvolveImmune Therapeutics, and Trefoil Therapeutics, and a board observer at several private biotechnology companies. Prior to Solasta Ventures, he spent more than twenty years in alternative (VC/PE) investments and healthcare corporate banking where he took numerous responsibilities in portfolio management, deal structuring, and fundraising. His previous experience includes venture investment management at Kibo Capital, the first venture fund in Korea; portfolio management with RBS Healthcare Banking Group; and venture accelerator program at Berwind Private Equity, a multi-generational family office located in Harvard, Massachusetts.
Mr. Yoon earned his M.B.A. from Babson College, M.S.F. from Boston College and B.S. in Chemical Engineering from Yonsei University in Seoul, Korea.
Derek Yoon, MSF, MBA
As President & CEO, Mr. Yoon leads Solasta Ventures (formerly known as Aju IB Investment), one of the leading venture capital firms in South Korea. Based in Boston, Massachusetts, Mr....
Scientific Advisors
- Richard Flavell, PhD
Yale – Sterling Professor, Chairman Emeritus of Immunobiology, Howard Hughes Medical Institute Investigator - Susan Kaech, PhD
Salk Institute – Director NOMIS Center for Immunobiology and Microbial Pathogenesis, NOMIS Chair(Note: Participation by Dr. Kaech as a member of the Scientific Advisory Board does not constitute or imply endorsement by the Salk Institute for Biological Studies)
- Nils Lonberg, PhD
Executive in Residence – Canaan Partners
Former SVP Biologics Discovery, Oncology Discovery – Bristol-Myers Squibb Partnered w/ Jim Allison on CTLA-4 drug development - Mario Sznol, MD
Co-Director, Yale Cancer Immunology; Skin Cancer Institute
Leader of the Melanoma/Renal Cancer Translational Team, Former president Society of Immunotherapy in Cancer (SITC)






