Senior Scientist, Translational Science

Feb 14, 2023

Who We Are:

EvolveImmune Therapeutics is a next-generation immunotherapy company based in Branford and Farmington, CT. EvolveImmune is harnessing its ‘Immunology First’ approach to create first-in-category cancer medicines which aim to transform the lives of patients by delivering superior, long-term outcomes compared to current anti-cancer therapies. The EvolveImmune team has established a first-in-class and highly differentiated tumor-targeted T cell costimulation platform designed to re-invigorate adaptive immune responses in solid tumors. In addition, building upon research that originated from the Sidi Chen Laboratory at Yale University, EvolveImmune is leveraging a novel in vivo CRISPR-based target discovery platform to develop a broad portfolio of first-in-class therapeutics for unmet needs in oncology and immune diseases.

The Role:

We are seeking a talented, highly motivated scientist to execute translational immunology and biomarker research to support IND enabling activities and planned phase I clinical studies in oncology. Experience in immune-assay development and validation is required. Expertise in human immunology and T cell immunobiology is preferred. The role involves experimental design (CRO and internal) and execution (bench work) as well as interpretation and presentation of results. This is an exciting opportunity for a highly collaborative and creative scientist who is eager to position novel immunotherapies in the cancer immunology treatment landscape. Close collaboration and matrix working with members of the Immunobiology, Biotherapeutics and Translational Science teams are expected. Evidence for a track record of scientific and/or project achievements is preferred. Strong verbal and written communication skills are expected.

For more information about EvolveImmune Therapeutics, please visit


· Design and conduct in vitro studies with an emphasis on immunological testing of human and animal samples using state-of-the-art techniques including immune cell functional assays, multi-parameter FACS, cell separation, multiplex assays, cell toxicity, proliferation

· Perform immune-monitoring related experiments of clinical samples (tumor, whole blood, PBMC, sera, etc.)

· Provide scientific input to optimize project progression

· Maintain records of experiments in electronic notebooks, analyze data and prepare presentations

· Deliver clear, concise presentations at portfolio and project meetings to enable organizational alignment

· Support the authoring of essential internal and regulatory documents

· Partner with Immunobiology, Biotherapeutics and Translational Science teams to ensure proactive sharing of scientific know-how across the organization

· Ensure compliance with all health and safety protocols


· PhD in immunology or a related fields with 1-3+ years of postdoctoral or industry experience

· Patient focused – dedication to enabling translation of preclinical research into impactful human therapies

· Proven track record in cellular immunology in translational setting demonstrating technical expertise in assaying immune cells in vitro and ex vivo

· Experience in the field of immune-oncology and large data analytics is a plus

· Capable of clarifying problems and working in collaboration with team members to identify solutions

· Strong verbal and written communication skills

EvolveImmune will provide a competitive compensation package based on the level of the experience of the candidate.

Principals only.

Qualified applicants should apply using this link.